Dr. Drang is having the same problem I have been having:
> I’ve been having a small but persistent audio problem that can be really annoying. Every few days, the audio controls in the Control Center stop working. Play/pause, volume, skip—none of them work. In and of itself, this doesn’t bother me much because I don’t use CC’s audio controls very often, but the bug goes hand-in-hand with another problem that bothers the hell out of me.
It is a pain in the butt[^fn1] and it seems like the only way you can fix it is restart your phone.
[^fn1]: It is especially frustrating when you are driving.